ENDOCRINOLOGICAL STUDIES ON ENVIRONMENTAL AND PSYCHIATRIC MENSTRUAL DISORDERS

Endocrinological disorders and celiac disease.

Celiac disease is a permanent intolerance to dietary gluten. Its well known features are abdominal symptoms, malabsorption of nutrients, and small-bowel mucosal inflammation with villous atrophy, which recover on a gluten-free diet. Diagnosis is challenging in that patients often suffer from subtle, if any, symptoms. The risk of clinically silent celiac disease is increased in various autoimmun...

Gender-related endocrinological dysfunction and mental disorders.

PURPOSE OF REVIEW The association between endocrine and neuropsychiatric disorders was established long ago, with solid evidence. According to a multidimensional model of mental disorders, one can conceptualize sex and gender-related endocrinological dysfunctions as a cluster of risk factors included in the biological determinants of those disorders. RECENT FINDINGS Gender and sexual dimorphi...

Menstrual disorders.

Menstrual disorders.

Menstrual disorders are very common in adolescence, and can be the cause of a significant amount of stress to both the patients and their parents. Variations of the menstrual cycle in this age are very broad and are mainly caused by the immaturity of the hypothalamic-pituitary-ovarian (HPO) axis. Amenorrhea (either primary or secondary), abnormal uterine bleeding and dysmenorrhea are conditions...

Update on treatment of menstrual disorders.

There is evidence from well designed randomised controlled trials that modern medical and conservative surgical therapies (including endometrial ablation) are effective treatments for heavy menstrual bleeding for many women. Submucous fibroids may be resected directly via the hysteroscope, reducing menstrual bleeding, although data are available only from case series. Endometriosis is common, m...